The Catenin-delta1 (Ab-228) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to catenin delta 1, CTNND1, p120(cas), p120(CTN), P120CAS, and p120ctn. This antibody recognizes Human antigen. The Catenin-delta1 (Ab-228) Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway By similarity. Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.Keirsebilck A., Genomics 50:129-146(1998).Nagase T., DNA Res. 4:141-150(1997).W.S., Sherwood J.K., Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases